Why there is no appetite suppression or even weight gain on Semaglutide for weight loss?

Semaglutide, a peptide drug approved by the FDA to treat type 2 diabetes and obesity, achieves weight loss by acting on GLP-1 receptors to control appetite. In short, Semaglutide allows you to reduce your food intake without feeling hungry, thus promoting weight loss. If you do not feel appetite suppression after using Semaglutide, you are still gaining weight, what is the reason?

First, Semaglutide doesn’t work for everyone. If you have been using Semaglutide for a long time and the dosage has been increased to the highest level and still has no effect, then there is no need to continue using Semaglutide. If you’ve just started using Semaglutide and haven’t seen results yet, that’s our topic for today.

Many people start Semaglutide treatment after hearing about the weight loss results of Semaglutide from various sources. Once you don’t see results in time, you start to wonder if Semaglutide is useful.

Related to the dose of Semaglutide

The therapeutic dose of Semaglutide is 1.7-2.4mg per week. To reduce side effects and allow the body to adjust to the drug, it is usually titrated from a low dose to a therapeutic dose. In the process of titration, it takes several months to experience, so during this time, the effect of the drug is not obvious.

Some people start with 0.5mg, continue for four weeks, then increase to 0.75mg, and then to 1mg. Others start at 0.25mg, increase to 0.5mg after a month, and then need to increase to 0.75mg after four weeks on 0.5mg, and then 1mg. However, when he was still at 0.5mg and did not see appetite suppression and weight loss, he became suspicious of the effects of Semaglutide.

In fact, when the user is still at 0.5mg, this dose has not reached the therapeutic dose, so the suppression of appetite may not be significant. If you still maintain your previous eating habits and caloric intake, you will gain weight in the past, but now even on Semaglutide, the caloric surplus will still cause weight gain.

Therefore, on Semaglutide, it is necessary to remain patient and wait for the actual dose to reach the therapeutic dose.

Individual related

The actual effect of Semalutide varies from individual to individual, which is also the reason why some people cannot achieve weight loss by using Semaglutide. Some people feel the effects and start to lose weight when they start using Semaglutide, while others need to reach a therapeutic dose to lose weight. Our bodies are complex, and many drugs take time to show their effects.

If you have increased your dose to a therapeutic dose and are still not losing weight, it is time to consider whether Semaglutide will work for you.

Develop good eating habits in semaglutide for weight loss

Many people who are severely obese are unable to control their desire to eat. Semaglutide makes it easier for users to fill up and lose the desire to overeat, thereby starving them to their target weight. This also shows that the basic weight loss is to reduce the intake of calories.

The common thinking of Semaglutide users is: because I can’t control my desire to eat more, use semaglutide to help control the appetite, and if the appetite is not best controlled on Semaglutide, then Semaglutide is not working well.

While using Semaglutide, we can rely on it to some extent to control our food intake, but it is still important to develop healthy eating habits. If you stop using Semaglutide after you have successfully lost your goal weight, it is still possible to regain the weight if you still eat excessive calories and do not exercise. Good eating habits can help you keep the weight off without gaining it back after you’ve lost it.

Therefore, in the process of losing weight, you should be patient and pay attention to the cultivation of habits.