Categories
- Blog (756)
- Customer Purchase (378)
- Best Sarms stack (6)
- Weight loss peptide (38)
- Other supplements (7)
- Home made (5)
- Testosterone & TRT & AAS (58)
It is better known by its brand name Proviron than Mesterolone.
Mesterolone is an oral androgen and anabolic steroid (AAS) drug developed in the 1960s and introduced for medical use by Schering in 1967 under the brand name Proviron. It is a derivative of DHT, does not produce estrogen, has weak androgenic and anabolic effects, is used primarily to treat low testosterone levels, and has also been used to treat male infertility.
Product Name: Mesterolone
Other name: Proviron
CAS : 1424-00-6
MF: C20H32O2
MW: 304.47
EINCES: 215-836-3
Purity: 99%Min
Appearance: White powder
Package: 10g/bag or as customers’request.
Test Method: HPLC
Mesterolone is an androgen receptor (AR) agonist and has relatively low androgen and anabolic potency due to the inactivation of 3α-hydroxy steroid dehydrogenase (3α-HSD) in skeletal muscle tissue, similar to DHT and Mestanolone. However, it still shows a greater ratio of anabolic activity to androgen activity compared to testosterone.
Mesterolone is not a substrate for 5α-reductase because it has been reduced by 5α-reductase. Therefore, there is no enhancement in androgenic tissues such as skin, hair follicles, and prostate.
Mesterolone is not a substrate for aromatase and cannot be converted to estrogen. As a result, Mesterolone is not associated with estrogen side effects, such as gynecomastia and fluid retention.
Mesterolone is not a 17α-alkyl compound, so it has no hepatotoxicity.
Mesterolone is not metabolized by the liver and has significant oral activity. Mesterolone is one of the few oral AAS that are either 17 alpha-alkylated or not. Mesterolone can be used in high doses or for longer periods of time depending on the individual situation.
Mesterolone has a very high affinity for human serum sex hormone binding protein (SHBG), and therefore, it may replace endogenous testosterone in binding to SHBG, thereby increasing serum free testosterone concentration. Similarly, when Mesterolone is preferentially combined with SHBG, the activities of other AAS can be increased to make other AAS play their full role.