What is ester, why add it to steroids?

When we get ready to use Boldenone for bodybuilding, what we find is, There are several types of Boldenone available, including Boldenone acetate, Boldenone cypionate and Boldenone undecylenate. When we get to know the relevant information, we will find that they are Boldenones with different half-lives, and the use effect is basically the same. Similarly, common anabolic steroids such as Testosterone, Trenbolone, Nandrolone, Metenolone all have different ester forms. So, what do these esters do, and why add it to steroids?

What is Steroids ester?

Steroid esters themselves are naturally present in the body. Scientists first discovered that many cytochrome steroid producing enzymes use steroid sulfates as substrates, and dehydroepiandrosterone sulfate is one of them. Later, biological synthesis studies showed that maternal steroids could be converted into precursor drugs through esterification of fatty acids on steroids, which could not only prolong the duration of steroid action, but also improve the metabolic stability, water solubility or lipophilicity and oral bioavailability of steroids.

Take testosterone, the body’s basic hormone and the most commonly used anabolic steroid by bodybuilders. However, testosterone has a very short half-life, about 5-7 hours for oral testosterone and no more than 1 day for injection. Testosterone’s half-life is increased by up to 15 days (Testosterone Undecanoate) when the corresponding ester is added to testosterone, so frequent injections are no longer necessary when bodybuilder uses testosterone ester.

At the same time, oral bioavailability of testosterone is very low due to extensive first-pass metabolism and is not suitable for oral use. Attaching a corresponding ester to testosterone also alters its bioavailability. Testosterone Undecanoate is an oral testosterone ester with excellent bioavailability.

The ester added to the steroid, increases the water solubility or lipophilicity of the steroid, making it easier for Bodybuilders to obtain injectable steroids for better bodybuilding results.

Different steroids with the same ester

There are many types of injectable steroids, and we can find that each injectable steroid has several different ester forms, which actually exist for the convenience of bodybuilder. We will find that when steroids  use for medical purposes only a single steroid ester form is often use and when bodybuilders use them a variety of ester forms.

This is also because Bodybuilders usually do not use a single ester form. When they stack different steroids for better results, if all the stacking steroids have the same half-life, bodybuilder can inject all the steroids at the same time. They don’t forget the injection time because of different half-lives. Bodybuilder will also stack different forms of esters of the same steroid so that the steroid is continuously release in the body, which can maintain stable high hormone levels in the body for a long time. Therefore, the different ester forms of steroids greatly facilitate the use of bodybuilder.