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Testosterone is primarily for the treatment of hypogonadism and as a hormone therapy for sex transition.
Testosterone is a hormone that plays a key role in the development and maintenance of male reproductive tissue and secondary sexual characteristics. It also has important effects on a variety of biological functions, including muscle mass, bone density, red blood cell production, and mood regulation. Testosterone levels naturally decline with age and can also be affected by diseases and impairment of certain organ functions, which can lead to a variety of symptoms and health problems.
Hypogonadism is mainly due to a person’s physical condition or advancing age, in which case a doctor may begin testosterone replacement therapy (TRT). This treatment helps relieve symptoms associated with low testosterone.
For individuals receiving sex-confirming hormone therapy, testosterone induce physiological changes in masculinization. This is a fairly small group, and TRT is usually the only way most people get testosterone prescriptions.
However, the conditions for issuing TRTS are becoming stricter. In 2015, the FDA redefined the indications for TRT products, stating that testosterone replacement therapy products should be avoided in patients with testosterone deficiency who do not have related diseases or have testosterone deficiency due to aging. This change prevents patients with testosterone deficiency due to aging from getting testosterone replacement treatment products from their doctors.
Because of the FDA review, there is data showing that TRT can increase cardiovascular risk. Therefore, the use of TRT should be cautious. Additional data showed that the probability of cardiovascular risk was similar between TRT and placebo. The increased cardiovascular risk associated with TRT may be related to the use of high doses.
Those who disagree also have experimental data showing that low testosterone levels can lead to death and coronary artery disease, and that testosterone supplementation can reduce mortality, myocardial infarction and stroke rates.
Today, testosterone prescribing practices vary from place to place, and you may come across places that are particularly strict, while others are relatively liberal. Subject to various restrictions, normal bodybuilder basically can not get testosterone from the hospital, so many people will get testosterone through various channels.
In addition to testosterone and testosterone esters, many testosterone derivatives perform similar or even better effects than testosterone. Including Nandrolone, DECA, Masteron, etc., in addition to injection use, there are oral products including anavar, dianabol, etc.
In fact, the testosterone dose requirements of Bodybuilders are much higher than TRT. The normal testosterone dose for TRT is 125-200mg per week, while the starting testosterone dose for bodybuilders is usually 500mg per week, so the testosterone dose obtained through TRT is often not enough to support bodybuilders to gain the muscle mass they need.