Semaglutide is a GLP-1 single receptor agonist, Tirzpatide is a GLP-1 and GIP double receptor agonist, and Retatrutide is a GLP-1, GIP and GCG triple receptor agonist. From their mode of action, we would think that there is a progressive relationship between them. If there is a progressive relationship between modes of action, does that mean there is also a …