What is Neuropeptide kisspeptin? Neuropeptide Kisspeptin-10, also known as kiss1, was first identified in 1996 as a transfer suppressor in human cell lines. The Kiss1 gene encodes a protein composed of 145 amino acids. In the human body, this protein is processed into a 54-amino acid peptide called kisspeptin, which, like several other neuropeptides, has a unique RF-amide motifs in …