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The most commonly used drugs in PCT, short for post-cycle therapy, are Tamoxifen, Clomid and HCG.
Tamoxifen, also known as Nolvadex, is a selective estrogen receptor modulator (SERM) along with Clomid. The effects of both are basically similar, Tamoxifen is milder and has fewer side effects than Clomid.
Since the main effect of anabolic steroids used in bodybuilding on men is to inhibit the secretion of endogenous testosterone, the main purpose of PCT is to restart the secretion of endogenous testosterone. It helps stimulate the release of luteinizing hormone LH and follicle-stimulating hormone FSH, which in turn stimulates the testicles to produce testosterone.
Tamoxifen is FDA-approved for the treatment of breast cancer, so there is no definitive method of using Tamoxifen for PCT, including dosage. The dosage of Tamoxifen is related to the dosage, cycle, and pattern of use of anabolic steroids used by bodybuilder or other bodybuilding supplements such as sarm. There is no specific dosage.
In bodybuilders’ experience, when using Tamoxifen in PCT, the dosage range is usually 20mg to 40mg per day, take it orally. The service cycle is generally 6-8 weeks. bodybuilder typically chooses to start the PCT with a dose of 40mg per day and reduce the dose to 20mg per day after half the cycle.
Because Tamoxifen has a long half-life and its metabolites are active, a moderate dose of 20mg is sufficient. If taken in high doses, it may increase the occurrence of side effects. Most Bodybuilders, when choosing a daily dose of 40mg, will usually split the daily dose, i.e., once in the morning and once in the evening. Breaking up high doses of Tamoxifen reduces the likelihood of side effects. Possible side effects of Tamoxifen include headache, nausea, dizziness, vision problems. It can also put pressure on the liver when taken at high doses over a long period of time.
Tamoxifen acts as an anti-estrogen, and when used in PCT it continues to act on the breast, helping to reverse male breast development (gyno).
If circulating anabolic steroids have little effect on bodybuilder, Tamoxifen in PCT is sufficient. If the bodybuilder’s endogenous testosterone is severely inhibited, Clomid and HCG are used.
In summary, tamoxifen 20 mg daily for 6 to 8 weeks is very effective for post-cycle therapy. When combined with Clomid and hCG, it helps stimulate testosterone production after the steroid cycle, restoring normal hormonal function. Proper dosage and cycles are important to maximize benefit and minimize side effects.