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Any drug has its “possible” side effects, so why use the word “possible”? Because the prerequisite for side effects is often related to dosage and long-term use. Oxandrolone is approved by the FDA for medical use, and today we’re going to talk about some of its potential side effects.
As anabolic androgen steroids, androgen side effects are an inevitable problem in the use of all AAS.
In women, a common androgen side effect of AAS is the possible development of masculine or even irreversible masculine characteristics, such as deep voice, hair growth, abnormal menstruation, and male pattern hair loss.
In men, a common androgen side effect in addition to acne is testosterone suppression. Testosterone inhibition in men is influenced by HPTA (hypothalamic-pituitary-testicular axis). When the level of exogenous androgen increases, the body will reduce the secretion of testosterone through HPTA, thus reducing the level of endogenous testosterone. Long-term testosterone inhibition will also lead to testicular atrophy. However, Oxandrolone is a milder version of AAS, and its effect on HPTA is much less than that of other AAS. When Oxandrolone is taken at normal dose and cycle length, there is virtually no shutdown of endogenous testosterone secretion.
The opposite of androgen side effects is estrogen side effects. Although you are taking androgens, androgens are converted to estrogen by aromatase in the body, which can cause estrogen side effects. Oxandrolone, as a derivative of DHT, does not interact with aromatase and, therefore, does not convert to estrogen. So Oxandrolone alone doesn’t have to worry about estrogen side effects.
Hepatotoxicity is a common side effect of oral AAS, as is Oxandrolone. However,Oxandrolone is much less toxic to the liver than some other oral AAS. However, the possibility of liver damage is very small with normal dosage and periodic use. However, bodybuilder with a bad liver is best not to use it. If any discomfort occurs during use, seek medical attention immediately.
Oxandrolone may also increase the amount of low-density lipoprotein (LDL) and decrease the amount of high-density lipoprotein (HDL) in the blood. It needs to be used more cautiously in patients who have a history of cardiovascular disease or are at risk for cardiovascular disease. The blood should be checked regularly and the dose adjusted.
In fact, as a mild AAS,Oxandrolone is relatively safe. It has no estrogenic side effects, very few androgenic side effects, and less hepatotoxicity than some other AAS.