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In the use of bodybuilding supplements, the most direct impact on the body is the inhibition of their own testosterone level, is there a growth of muscle mass without affecting their own testosterone levels of supplements?
AAS is an exogenous androgen. The use of exogenous androgen in the bodybuilding cycle will definitely affect the secretion of testosterone. Tijdens dit proces, the level of testosterone in the body may still in homeostasis, but this balance is not controll by HPTA(hypothalamus-hypofyse-testiculaire as), but the secretion of endogenous testosterone gradually decreases, and AAS supplements this part of testosterone and balances the levels of testosterone in the body at a higher level.
SARMs are not androgens, and the use of sarms in the bodybuilding cycle theoretically does not affect endogenous testosterone levels. Echter, this is not the case. sarms work by binding to androgen receptors, and by taking up a portion of the androgen receptors, the body produces an extra portion of testosterone. The brain detects that there is more testosterone secreted and reduces testosterone production. Daarom, if you use sarms, you will still reduce some of your own testosterone levels.
Since both AAS and SARMS use reduce endogenous testosterone levels, is it possible to maintain normal testosterone levels in the process? It is possible to use these supplements to stack testosterone to replenish the testosterone that less produced. But in doing so, it still suppress the testosterone level.
So bodybuilders began experimenting with the use of gonadotropins in the cycle, which unblocks the inhibition of HPTA by high testosterone levels so that testosterone is release continuously . Enclomiphene is commonly to maintain the level of endogenous testosterone.
In addition to natural additives and strengthening exercises, only a few that are classified as sarms are other receptor agonists (which do not act on androgen receptors) that do not affect testosterone levels. GW501516, bijvoorbeeld, helps build muscle by regulating metabolism to boost energy levels and endurance. Echter, these supplements are not as effective as sarms and AAS in building muscle.