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For experienced Bodybuilders, it is rare to use only one AAS in their cycle, and Mesterolone/Proviron is a proper AAS for stacking.
Studies have shown that long-term use of high doses of Mesterolone has no serious inhibitory effect on endogenous testosterone. A daily dose of 150mg or less of Mesterolone has no significant inhibiting testosterone results. The normal dose did not inhibit HPTA. As a result, some Bodybuilders try to use Mesterolone during PCTS to maintain revenue. Later studies have shown that Mesterolone inhibits LH(luteinizing hormone) in some cases. Because Mesterolone has a high affinity with aromatase, the use of Mesterolone by bodybuilder during the AAS cycle can act as an anti-estrogen agent. Although Mesterolone is not as active as Aromasin, Arimidex or Letrozole as an aromatase inhibitor, it is still effective and can act as a good AI. Its strength as an aromatase inhibitor is comparable to that of Arimidex, but slightly lower. Therefore, bodybuilder can use it as an alternative to aromatase inhibitors during the AAS cycle.
This property makes Mesterolone a proper AAS for stacking . Use Mesterolone stacke with AAS that are easily be converte to estrogen by aromatase, such as power tonic, testosterone and its ester compounds, Norone, or Equipoise. bodybuilder can get a stiffer look with more veins. Less swelling of the muscles.
Mesterolone also has a very high affinity with sex hormone binding protein (SHBG), a hormone responsible for reducing the amount of free testosterone circulating in the body. When bodybuilder adds Mesterolone to the AAS stack, Mesterolone binds to SHBG preferentially. The release of more free testosterone also increases the activity of other AAS, allowing other AAS to function.
Mesterolone has weak synthetic metabolism and androgen, does not inhibit endogenous testosterone, and does not help muscle gain as much as some other AAS have high synthetic metabolism. As a result, when use Mesterolone alone, the muscle gain was not too much. However, Mesterolone does not aromatize and has a high affinity with aromatase, which prevents other AAS from being aromatized. Mesterolone is preferre to combine with SHBG, so that other AAS can play a better role. Mesterolone does not inhibit endogenous testosterone and does not give bodybuilder symptoms of low testosterone; Mesterolone, as an oral AAS, is easy to use without the pain and risk of infection associated with injection use. Mesterolone brings all kinds of benefits to show that it is a proper AAS for stacking.
Mesterolone acts as oral AAS and is stacked with other AAS or SARMs to avoid water retention for maximum muscle mass gain and a more aesthetically pleasing muscle appearance.