HCG 5000iu injection is easy to buy on line for man who need it for their bodybuilding cycle.
What is human chorionic gonadotropin (hCG)?
- hCG is a glycoprotein composed of 237 amino acids.
- hCG is a hormone used by the mother to recognize pregnancy, which is produced by trophoblast cells around the growing embryo.
- hCG is an analogue of luteinizing hormone (LH).
- hCG has a similar effect to LH, which is used to induce ovarian ovulation and testosterone production in the testes.
- In the male bodybuilder, hCG for man helps restore and maintain testosterone production in the testis by imitating LH and triggering the production and release of testosterone.
There are two sources of hCG, one is direct extraction (it can extracte from animal pituitary or urine of pregnant women), and the other is produced by recombinant DNA technology. The hCG prepared by the two main methods has some technical differences, but has no impact on users. Recombinant hCG only consists of dimer hCG with two subunits. The hCG obtained by direct extraction may also include the subunit as a monomer.
The hCG provided by Pubergen, Pregnyl, Follutein, Profasi, Choragon and Novarel are extracted from the urine of pregnant women, and the hCG of Ovidrel is produced by DNA recombination technology.
HCG development history
Before HCG being used in the bodybuilder, it is also a familiar product for ordinary people. Let’s learn about the history of hCG.
Treatment of fertility related diseases – Weight loss – PCT drug
Treatment of fertility related diseases
HCG was first discovered in 1920, and it was confirmed as a pregnancy hormone 8 years later. The first commercial hCG drug was extracted from animal pituitary and produced by Organon.
In 1931, Organon named the hCG product Pregnon, which was later renamed Pregnyl due to commercial disputes.
In 1940, another technology was used to produce hCG by filtering and purifying the urine of pregnant women.
Early hCG drugs were more widely used than today. In the product literature of the 1950s and 1960s, it was pointed out that hCG could be used to treat uterine bleeding and amenorrhea, Flemish syndrome, cryptorchidism, female infertility, obesity, depression, and impotence. Another good example is the description in Glukor’s user manual in 1958: “It is three times more effective than testosterone, and can be used for middle-aged men in menopause and elderly men in aging, which is helpful for the treatment of impotence, angina pectoris, coronary heart disease, neuropsychiatric diseases, prostatitis and myocarditis.”
At present, the use of hCG approved by FDA is limited to male hypogonadism, cryptorchidism and female anovulatory infertility.
Weight loss
HCG has been widely used to treat obesity. Albert TW Simeons, a British endocrinologist, proposed that hCG should be used as an auxiliary means of ultra-low calorie diet (less than 500 calories). Simeons found in the study that pregnant women with a low calorie diet treated with hCG and those with pituitary problems choose to lose fat rather than muscle.
In 1954, Simeons published a book entitled Pounds and Inches, which aims to fight obesity.
Simeons practices in Salvator Mundi International Hospital in Rome, Italy. It is recommended to inject low dose hCG (125IU) every day in combination with a customized ultra-low calorie diet (500 calories/day, high protein, low carbohydrate/fat) to reduce fat without losing muscle. This trend is rapidly becoming popular, and people all over the country have started to control their diet calories while injecting hCG.
In 1957, it became the most commonly used prescription drug to treat obesity. The FDA warns consumers who use Simeons diet that too strict caloric control will cause human muscles and organs to sacrifice some substances to obtain the necessary protein every day, which is even more costly.
In 1974, FDA received many complaints and had to stipulate that all hCG specifications should include the following statements:
“These weight reduction treatments include the injection of HCG, a drug which has not been approved by the Food and Drug Administration as safe and effective in the treatment of obesity or weight control. There is no substantial evidence that HCG increases weight loss beyond that resulting from caloric restriction, that it causes a more attractive or “normal” distribution of fat, or that it decreases the hunger and discomfort associated with calorie-restrictive diets.”
— 1976 FDA-mandated disclaimer for HCG diet advertisements
Despite this, some clinics still advocate the use of hCG to help dieters lose weight.
PCT drug
Now we know that hCG is used as a pct plug in the pct cycle In fact, there is no word pct for bodybuilder from 1960s to 1980s. It was not until the 1980s that hCG became popular in the body builder, and at that time the body builder usually used hCG as the only drug for pct.
How about the use of HCG 5000iu injection for man duiring PCT cycle?
FDA approved that women use hCG to help treat infertility and men use hCG to treat hypogonadism.
Why can hCG treat male hypogonadism? Because hCG stimulates Leyding cells to synthesize testosterone. Testosterone in the testis is necessary for supporting cells to produce sperm.
Why need hCG for man?
Androgen and muscle growth and maintenance are inseparable, testosterone is the most common androgen. In order to increase muscle, the bodybuilder will supplement exogenous androgens to help build muscle.
When exogenous androgens enter the male body, the body will think that the testosterone level in the body is enough, and will gradually inhibit the secretion of endogenous testosterone, or cause the closure of the hypothalamus pituitary gonad axis (HPGA). When this situation actually occurs, when the body builder stops the intake of exogenous testosterone, the level of endogenous testosterone in the body will not be enough to maintain the normal function of the body, resulting in low testosterone symptoms.
HCG stimulates the testes to synthesize testosterone, which helps the testosterone level recover as soon as possible. Therefore, in the pct cycle, bodybuilders use hCG for man.
How HCG restore man’s testosterone level?
Normally, LH controls the production of testosterone in the testis. LH usually travels from the pituitary gland through the blood stream to the testes, where it triggers the production and release of testosterone. HCG mimics LH and triggers the production and release of testosterone to help restore and maintain testosterone production in the testis.
Hypothalamus pituitary gonad axis (HPGA) is inhibite for a long time. When endogenous testosterone secretion gradually decreases, testicular atrophy will occur. In addition to appearance problems, testicular atrophy may also endanger health and fertility. The addition of hCG to pct can help maintain and restore the size of testis. Some bodybuilders will add hCG to the normal bodybuilding cycle to prevent testicular atrophy.
However, high dose of hCG will increase the activity of aromatase, which will convert androgen into estrogen in the body. The increase of estrogen level will be accompanied by the corresponding side effects of estrogen.
Therefore, the male bodybuilder needs to control the dosage and add aromatase inhibitor in the process of using hCG for man.
When HCG 5000iu iis needs for man in PCT cycle?
If using AI and SERM cannot restore the natural testosterone level , try hCG 5000iu for man.
Body will recover testosterone level by itself normally
The hypothalamus pituitary testis axis, or HPTA for short, regulates the production of the body’s natural testosterone.
When the level of testosterone in the body is insufficient, the hypothalamus will release GnRH (gonadotropin) when it senses that the human body needs more testosterone. GnRH sends information to the pituitary gland, which releases luteal hormone (LH). The LH reaches the testes through the blood and stimulates the testes to secrete testosterone.
When the level of testosterone in the body is sufficient, the negative feedback mechanism of HPTA axis will ewduce the secretion of testosterone .
Anabolic steroids (AAS) inhibit testosterone secretion by negative feedback mechanism of HPTA axis. Exogenous AAS supplementation will make the body mistakenly think that the testosterone level in the body is enough, thus stimulating the negative feedback mechanism of HPTA axis, so that the secretion of natural testosterone becomes less and less.
When stop AAS, the body will start HPTA and produce testosterone when it senses that testosterone is insufficient. However, the recovery of HPTA axis is a very slow process. In the process of HPTA axis recovery, the following situation will occur – the pituitary releases LH, but the natural testosterone level does not rise.
A 1975 study showed this. A male bodybuilder continued for 21 weeks, injected 250mg testosterone heptanoate every week, stopped AAS injection, and used SERM to enter the pct. Although the LH level rose rapidly in the pct cycle, the natural testosterone level remained almost unchanged for a long time.
This is due to atrophy of testis and desensitization of LH.
In this condition, need use HCG
Anti estrogen drugs, such as Clomid and Novadex, promote the secretion of LH by blocking the negative feedback of estrogen. Therefore, after using anti estrogen drugs, we can see the rapid increase of LH level However, due to testicular atrophy and desensitization of LH, the natural testosterone level did not recover rapidly as expected.
At this time, for man, use inject hCG to help restore natural testosterone levels.
HCG for manstimulates the testes to secrete testosterone by imitating the role of human natural LH. Moreover, the level of androgen and estrogen in the body doesn’t affect hCG , which helps the rapid recovery of testicular quality and function, thus helping to produce testosterone more quickly.
Therefore, when the testis of the bodybuilder has become smaller, or after using AI and SERM as pct, the LH level increases, but the serum testosterone level does not recover in time, should inject hCG for man . At the same time, also need use anti estrogen drugs.
HCG dosage and cycle of Bodybuilder
We often hear about hCG from the bodybuilder, but the bodybuilder does not use hCG to increase muscle.It uses hCG to help maintain, increase or restore endogenous testosterone production. Usually use it in our PCT cycle. Of course, some times also use it in the Steroids cycle when necessary. At this time, we need to pay attention to the difference between the use times and doses of the two.
1.During Pct cycle hCG dosage
When using hCG for pct cycle, usually don’t use hCG alone. Although in the 1990s, a large number of bodybuilders used hCG as the only pct drug. This is because hCG only simulates the role of LH, stimulating the testes to produce testosterone, and cannot improve the level of LH. On the contrary, a large number of misuse of hCG may hinder the recovery of HPTA (hypothalamic pituitary testicular axis).
The pct cycle length of the Bodybuilder usually lasts 4-6 weeks.
In pct cycle, SERM Novadex is usually used together with hCG. Research shows that hCG and Novadex have synergistic effects in stimulating endogenous testosterone production and promoting the recovery of endogenous testosterone level as soon as possible. Moreover, Nolvadex can also prevent high-dose hCG inducing desensitization of Leydig cells, because Nolvadex inhibits hCG inhibition 17 α Hydroxyprogesterone is converte to testosterone.
Studies have shown that the use of hCG can increase the expression of aromatase in the testes, thus leading to an increase in estrogen levels. Therefore, also needs to use hCG with aromatase inhibitors (AI).
Common AI include letrozole, anastrozole and Aromasin (exemestane). Studies have shown that when using letrozole or anastrozole combination with SERM Novadex, Novadex reduces their plasma concentrations.
Therefore, in order to reduce the increase of aromatase activity caused by hCG, the best choice of aromatase inhibitor is Aromasin
hCG dosage
The dose of hCG for the purpose of restoring endogenous testosterone level in pct cycle is 500IU/day.
Although SERM is helpful to promote the release of LH and FSH and increase endogenous testosterone secretion. However, it has just ended the steroid cycle, and has a certain inhibition effect on the release of LH and FSH from pituitary. Therefore, in the weeks before the start of pct cycle, the high dose and dense use of hCG will help to rapidly stimulate the testes to start secreting testosterone.
How to use hCG in PCT cycle?
We should perform Pct after the last injection/oral administration of AAS. Assuming that the pct cycle is 6 weeks, the following are the hCG pct cycles:
First cycle run as 1-3weeks,using hCG combine with Novadex. The dosage of hCG was 1000IU three times a week, and the dosage of Novadex was 20mg/day. 4-6weeks, stop using hCG and start using Novadex for three weeks at a dosage of 20mg/day.
Second choice is,1-3 weeks, using hCG, nolvadex and clomid. The dosage of hCG was 1000 IU three times a week, the dosage of nolvadex was 20 mg/day, and the dosage of clomid is 50 mg/day. 4-6 weeks, stop using hCG , and continue to use nolvadex 20 mg/day and clomid 50 mg/day for three weeks.
2.Steroid cycle hCG hCG for man dosage and cycle
Although we cannot use hCG to grow muscle, only use it in pct cycle. However, in some cases, the bodybuilder will also add hCG to the stereoid cycle
In the steroid cycle, if the cycle is short, there is no need to use hCG . If the cycle is long (more than 12 weeks), or the individual testosterone level is very easy to inhibite or turn off, needs to add hCG for man.
In the long cycle, due to desensitization to gonadotropins, testicular atrophy can lead to the difficulty of hormone recovery during pct. In order to maintain testicular function during the steroid cycle, the bodybuilder will add hCG to the steroid cycle. At this time, hCG is as an auxiliary drug.
Generally, HCG has a fixable dosage. Inject hCG once or twice a week at a dose of 250-500IU. When using hCG in a steroid cycle, the maximum dose should not exceed 500IU/week.
How to buy best quality HCG for sale online?
As a manufacturer, we test the quality through simple and direct methods, instrument testing.
As an extract, HCG is not a single compound, so its detection method is not only our common Hplc report. Of course, the quality standard does not depend on purity.
When we buy HCG, the unit of the product is IU, and the common specification is 5000IU.At present, the two common specifications on the market are 2000IU/vials and 5000iu/vial It is better to choose 5000iu for effect. It is the simplest and most direct way to judge the quality from the product specifications.
I think you will also have more ways to test yourself. If the method is correct, even with a pregnancy test stick, you can also test the quality.