Growth hormone releasing hormone Sermorelin acetate and Tesamorelin, which is better?

Compared with the different action modes of Sermorelin acetate and HGH, the action modes of Sermorelin acetate and Tesamorelin could be said to be exactly the same. Sermorelin acetate and Tesamorelin are both analogues of growth hormone releasing hormone (GHRH), and both work by stimulating the synthesis of HGH(growth hormone). So how do I choose between these two peptides?

Different structure

The most direct difference between Sermorelin acetate and Tesamorelin is that both of them derive from the structure of GHRH, in which Sermorelin acetate intercepte 29 amino acid sequences of GHRH and retain the ability of GHRH to stimulate HGH release. Tesamorelin has all 44 amino acid sequences of GHRH.

Different indication

Peptides Sermorelin acetate and Tesamorelin acetate are use to treat corresponding diseases, among which Sermorelin acetate is mainly for HGH deficiency in children and adults. Tesamorelin is primarily for excess abdominal fat in HIV patients with lipodystrophy.

From their indications, Sermorelin acetate has a different emphasis than Tesamorelin, which provides guidance on how to choose them.

When to choose Tesamorelin?

Mainly use Tesamorelin to reduce excess abdominal fat accumulation, so you should choose Tesamorelin when your main purpose is fat loss. HGH has the effect of altering body composition (reducing fat, promoting lean muscle mass gain), and in cases where body fat mass is evident, the use of Tesamorelin helps to reduce fat quickly. However, Tesamorelin acts through HGH, and in addition to reducing fat, it also has the benefits of HGH, including improved metabolism and protein synthesis, increased lean muscle mass, faster healing, and improved athletic performance.

When do I choose Sermorelin acetate?

We mainly use Sermorelin acetate for HGH deficiency, therefore, the benefits of using Sermorelin acetate are the benefits of HGH, except that Sermorelin acetate increases the level of autocrine HGH and does not increase the level of endogenous HGH to a superphysiological level. When bodybuilders use Sermorelin acetate, the main effect is to improve lean muscle mass, that is, to increase muscle mass while avoiding fat accumulation.

When bodybuilders aim to increase metabolism and build muscle, we can use sermorelin acetate, or use Tesamorelin acetate if you focus on fat reduction or cutting.