For sale best quality Anti-Obesity peptides AOD9604 with good price benefits and review

When we know that AOD means Anti-Obesity Drug, we should know it is a diet drug when the word “AOD9604” comes into view. After we know it is diet pills, why we choose AOD9604 from all diet pills? Before we consider why we chose AOD9604, we need to know: What is AOD9604?

What is AOD9604? 

First of all, AOD9604 s a Anti-Obesity drug, which is undisputed and completely true.

Why develop a individual peptide AOD9604 from GH? 

Since 1959, Raben and Hollenberg first documented that GH has a significant lipolysis effect in adults, proving that GH can inhibit the differentiation of fat cells, reduce the accumulation of triglycerides, increase lipolysis, and thus reduce the quality of adipose tissue, GH has also been used by some people for the purpose of fat reduction.

However, because GH also has a number of side effects, including glucose intolerance, insulin resistance, hypertension, and edema, these side effects have limited its development as a drug treatment for obesity.

Studies of the structure and function of synthetic fragments of hormone molecules have shown that large proteins may contain many discrete functional domains,

To control or influence a variety of specific physiological or biochemical actions. But identifying the functional domains of these fragments is not easy.

After many years of research on GH, it was finally confirmed that the multifunctional GH molecule also contains different functional domains. It has been reported that the amino terminus of HGH molecule is the functional domain of the insulin-like action of HGH molecule, while the carboxyl terminus (C-terminus) of HGH molecule is the functional domain of the controlling substance. That’s where the new small molecule peptide AOD9604 comes in.

What is AOD9604?

AOD9604 also call as Tyr-hGH 177-191. Because it is actually a C-terminal fragment of human growth hormone (HGH), prepared by solid-phase peptide synthesis, it contains an additional tyrosine at its n-terminal for peptide stabilization and cyclization by a disulfide bond between two cysteine residues. The result was a new peptide, AOD9604.

The C-terminal fragment of HGH (amino acids 177-191) is a structural region in HGH specifically responsible for lipids, which stimulates lipodecomposition and inhibits lipogenesis.

HGH, as a human growth hormone, has synthetic metabolic properties, and its benefits are very clear to us, including increasing height, increasing muscle, burning fat and so on. However, it also has certain side effects, including glucose intolerance, diabetes and insulin resistance, acromegaly, cancer, edema and hypertension.

For those who want to lose fat, nothing could be better than the fat-reducing properties of HGH while avoiding the possible side effects of HGH. Anti-Obesity AOD9604 was developed on this basis.

AOD9604 vs HGH 176-191

AOD9604 is also known as Tyr-hGH 177-191, which is very similar to HGH 176-191, and some people may confuse the two.

HGH 176-191 is more like a transition between HGH and AOD9604.

While HGH has reduced ester and many other benefits, AOD9604 focuses solely on fat loss and eliminates the side effects associated with HGH. HGH 176-191 is in the middle, which in addition to reducing fat, also stimulates IGF-1 secretion and increases blood IGF-1 levels. Therefore, HGH 176-191 will still affect the body’s glucose level and so on.

So Anti-Obesity AOD9604 is a more targeted peptide with fewer side effects. If your goal is to lose weight, then, of these three, AOD9604 is the obvious choice.

Anti-Obesity AOD9604 benefits

Anti-Obesity AOD9604 derive from HGH, which only retains the fat reduction function of HGH and avoids the possible side effects of HGH. By comparing its relationship with HGH, we can easily understand the benefits of AOD9604.

Fat reduction effect of AOD9604

Getting rid of unnecessary body fat is a dream for many people. Some people want to keep a slim shape by losing excess fat, while others want to keep healthy by losing excess body fat. However, as we age, the body’s natural hormone levels begin to drop, making it harder and harder to stay slim. Obesity affects not only the appearance, but also people’s physical health. Obesity is known to cause a variety of cardiovascular and cardiometabolic diseases, such as hypertension, coronary artery disease, diabetes, etc., which not only seriously reduce the quality of life, but sometimes even threaten life.

AOD9604 derivefrom 177-191 fragments of HGH, which can stimulate lipolysis and inhibit lipolysis.

Stimulating lipolysis

Studies have shown that AOD9604 breaks down fats and lipids by hydrolyzing triglycerides into glycerol and fatty acids.

In animal studies of AOD9604, After 19 days of treatment with a daily oral dose of AOD9604 of 500µg/kg body weight, reduce the weight gain by more than 50%. Experiments found that it reduced the size of the animals’ fat cells, and thus their body fat mass. The weight loss caused by long-term oral administration of AOD9604 also appears to be an increase in lipidolytic activity in adipose tissue. This also proves that AOD9604 reduces obesity by regulating lipid metabolism.

Inhibition of lipogenesis

Studies have shown that AOD9604 reduces fat production by inhibiting the activity of acetyl-coA carboxylase. Acetyl-coa carboxylase is A key enzyme involve in lipid synthesis.

Subsequent human trials include two intravenous and two oral administration studies. Two oral phase IIb studies were conducte in 300 and 500 obese adults to evaluate efficacy (weight loss), safety, and tolerability. In all human studies, AOD9604 was found to be safe and well tolerated.

Does not induce hyperglycemia and reduce insulin secretion

In addition to the lipid reduction function of AOD9604, it has also show that although it has a similar effect to HGH in lipid metabolism, it is independent of HGH in carbohydrate metabolism. Therefore, the use of AOD9604 only acts on fat, and does not affect the glucose oxidation and energy consumption of the human body. Long-term treatment will only increase the oxidation of fat, so there will be no glucose intolerance and insulin resistance problems that may occur when use HGH to reduce fat.

In the experiment, the blood sugar level of obese mice increased significantly after HGH treatment, while that of mice treated with AOD9604 did not change.

As shown in the figure, AOD9604 had no effect on circulating insulin levels in thin and obese mice. HGH also had no effect on plasma insulin levels in lean mice, but caused a staggering 66% decrease in circulating insulin levels in obese mice compared to pre-treatment levels.

It does not compete with HGH receptor and does not stimulate IGF-1 secretion

Unlike HGH, Anti-Obesity AOD9604 does not compete with HGH receptors and does not induce cell proliferation when it plays the role of lipid reduction.

The competitive binding test of HGH receptor clearly showed that HGH could compete with HGH receptor, while AOD9604 did not affect the concentration of HGH receptor.

Experiments have demonstrated that AOD9604 does not act through HGH receptors and is independent of the mechanism of action of HGH, so that it does not affect the action of HGH in vivo. At the same time, it does not stimulate IGF-1 secretion, and users do not have to worry about the possible side effects of cell proliferation such as acromegaly and tumors.

Beneficial to joint and cartilage health and repair

AOD9604 has a positive effect on cartilage and joint tissue repair in collagenase-induced rabbit model of osteoarthritis after intraarticular injection of Anti-Obesity AOD9604. Hyaluronic acid (HA) is a commonly use drug to treat OA in humans and animals. AOD9604 combined with AOD9604 injected into the joint has additional positive effects on cartilage and joint tissue repair.

1. It has a positive anabolic effect on chondrocytes. AOD9604 enhances key elements required for cartilage tissue formation by increasing the content of chondroproteoglycan (cell matrix) and collagen.
2. Enhance the differentiation of muscle progenitor cells (the cells that produce muscle cells) into muscle cells.

How do I use Anti-Obesity AOD9604?

Peptides are usually injection; Anti-Obesity AOD9604 is administer subcutaneously. It’s also available in oral form, but most people opt for injections.

AOD9604 is a small peptide that enters the bloodstream quickly and takes effect quickly. The best time to inject is in the morning, on an empty stomach. Giving an injection 30 minutes before eating in the morning will allow the body to make better use of AOD9604, which will ensure maximum results when it comes to weight loss. Of course, some people also choose to inject multiple times throughout the day to keep the effects going.

There is no fixed dose, but 300 micrograms a day is usually the most effective. In the course of using AOD9604, the maximum injection dose should not exceed 600 micrograms per day.

Anti-Obesity AOD9604 Side effects

Although, compared with HGH, it avoids many side effects that HGH may produce, very safe. However, before starting to use AOD9604, we should be aware of its potential risks and adverse effects to better use it.

There have been no reported side effects from AOD9604. As with all injection products, it may cause stomach upset, headache, pain at the injection site, redness, swelling and other reactions.

However, there have been no reported side effects or complications from AOD9604 compared to other medications, making it a good option for obese people who are looking for a safe alternative.

How long does Anti-Obesity AOD9604 take to see results?

The experiment showed that after 8 days of treatment with AOD9604, obese mice began to lose weight, which was due to the loss of body fat.

For most people, it takes up to 12 weeks to see results with AOD9604. However, as with all other fat reduction products, actual results vary from person to person. The amount of fat lost varies from person to person, the speed of results varies, and the individual’s physical condition can lead to different levels of success for different people. People who follow a healthy diet and exercise, for example, tend to get better results faster.

In addition, health risks, family history, other medications, age, and personal health factors will also determine your final outcome.

Anti-Obesity AOD9604 review

AOD9604 Recently be designated GRAS status for humans, which means it is safe. Although, as with any injection, it may cause pain and redness after injection, it is still a very safe peptide.

AOD9604 is a targeted small-molecule peptide derived from the molecular fragment of HGH that is focused on the single purpose of weight loss, thus avoiding the possible side effects of HGH use. Meanwhile, the extensive use of HGH by bodybuilder further proves the safety of AOD9604. AOD9604 is a safer compound than peptide HGH, so it is safe to choose it for fat reduction.

In addition to reducing fat, AOD9604 also has a certain effect on cartilage and joint tissue repair, helping to maintain bone health and repair after exercise.

In the famous case of Essendon, who was be claimed to have taken AOD9604 to enhance performance . Metabolic Pharmaceuticals CEO David kenley claimed he uses AOD9604 to help with soft tissue damage and post-motion recovery. So that those injured players can get back on the field more quickly. This demonstrates the bone benefits of AOD9604.