Enclomiphene vs Clomifene in PCT, is enclo works better?

The formula for PCT is Clomid+Nolvadex, where Clomid stimulates the release of endogenous testosterone and Nolvadex eliminates the effects of estrogen. However, an experienced bodybuilder would choose enclo when Enclomiphene vs Clomifene, and why?

What is Enclomiphene?

Enclomiphene used by Bodybuilders stands for Enclomiphene citrate, or simply enclo. Enclo, like Clomid, is a non-steroidal SERM(selective estrogen receptor modulator). Both work by antagonizing the estrogen receptor in the pituitary gland, reducing the negative feedback effect of estrogen on HPGA(hypothalamic-pituitary-gonad axis), thereby increasing the release of LH(luteinizing hormone) and FSH(Follicle-stimulating hormone), and promoting the production of testosterone.

Enclomiphene vs clomifene

Enclo is actually one of the two isomers of Clomid. Clomid itself is equivalent to 38% Zuclomifene and 62% enclomiphene. Of the two isomers, zuclo is an estrogen receptor agonist and enclo is an estrogen receptor antagonist, and they play opposite roles.

Since clomid has a half-life of 5 days, enclo has a half-life of about 10 hours, and zuclo has a half-life of 30 days, using Clomid to stimulate the release of testosterone in the daily oral dose is equivalent to stack zuclo, resulting in zuclo still exerting its estrogen effects after the drug done. Estrogen side effects for users.

The use of anti-estrogen Nolvadex is to eliminate the estrogen produced by the action of testosterone with aromatase, and when combined with Clomid for pct can eliminate the estrogen effect produced by zuclo.

Enclo is considered to be more effective than clomid in stimulating testosterone release in men because it does not cause estrogen problems when used directly.

In PCT, boosting testosterone production and eliminating estrogen side effects are usually done at the same time, so there is no problem with using Clomid+Nolvadex. If you only consider the promotion of testosterone production in the testes and the increase of endogenous testosterone levels, Enclomifene is more effective.

When to choose Enclomiphene?

Enclomiphene vs Clomifene, enclo is under study, and Clomid is a FDA approval and a market-proven SERM. Many people who using enclo tend to recommend it, believing that it works better. That’s right, if you don’t need to think about dealing with estrogen side effects, choose enclomifene better. You can also choose the general formula: Clomid+Nolvadex.