Clomid vs tamoxifen (Nolvadex)

What is Clomid?

Clomid is a non-steroidal SERM that promotes the release of more FSH(follicle-stimulating hormone) and LH(luteinizing hormone) from GnRH. FSH and LH help to increase the body’s testosterone level, which is very important when the bodybuilder is affected by exogenous AAS resulting in testosterone suppression.

In addition to increasing gonadotrophins, Clomid also binds to estrogen receptors, making it an important aid in treating pregnancy in both women and men, since excessive amounts of estrogen can affect our reproductive systems.

Clomid prevents this from happening by preventing estrogen from reaching the pituitary gland, where estrogen plays an antagonistic role.

What is Tamoxifen?

Tamoxifen is also a selective estrogen receptor modulator (SERM), which has certain estrogenic effects and is also used as an estrogen antagonist whose main effect is to eliminate the adverse effects of estrogen.

Tamoxifen works by binding to estrogen receptors in specific parts of the body. Tamoxifen mainly blocks estrogen in breast tissue and prevents it from attaching to breast cells, thereby preventing gynecomastia.

Tamoxifen works by binding to the corresponding estrogen receptor. Estrogen already present in the body can no longer bind to the estrogen receptor, thus reducing the effect of estrogen on breast tissue.

Clomid vs Tamoxifen

At pct cycle,bodybuilder typically uses Clomid with tamoxifen. Using both SERMs together, they can be safely administered at lower doses and provide significant results.

Gynecomastia is a common side effect of AAS. Although it is not a dangerous disease, it can have serious consequences for a person’s self-esteem. Gyno is caused by the production of estrogen in vivo after aromatase aromatase aromatase from exogenous AAS. Excess estrogen levels in men promote female characteristics, such as breast tissue development. In many cases, gynecomastia only results in the storage of tiny chunks of fat above or around a man’s nipple, or sometimes a swollen nipple.

Tamoxifen treats breast cancer by targeting breast tissue. Tamoxifen binds to estrogen receptors in the breast region, effectively preventing estrogen from acting there and thus preventing gynecomastia.

From the above we can know that Clomid vs tamoxifen both block the effect of estrogen. Clomid focuses on blocking the effects of estrogen gonadotrophins. Tamoxifen focuses on blocking the effects of estrogen on gynecomastia. When the pct cycle is mainly to solve the Gyno problem, tamoxifen alone can be used. Clomid is required if there is a problem with reduced testosterone levels after AAS cycle in addition to gynecomastia. Of course, Clomid also helps with gynecomastia.

In fact, most Bodybuilders choose to use both Clomid and tamoxifen in the pct cycle.