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Approved by the FDA for medical use in 1967, Clomid is a nonsteroidal selective estrogen receptor modulator (SERM) that treats male and female infertility primarily by stimulating sperm production and ovulation. The launch of Clomid ushered in the era of assisted reproductive technology.
Clomid blocks the production of estrogen and stimulates the hypothalamus and pituitary to produce gonadotropin-releasing hormone (GnRH), follicle-stimulating hormone (FSH), and luteinizing hormone (LH). These hormones promote follicle maturation and increase the chance of ovulation. Therefore, Clomid is using to treat infertility in women who do not ovulate or who ovulate too little, including women with polycystic ovary syndrome.
It can stimulate sperm production in men and assist in the treatment of male infertility.
It can be used to treat male hypogonadism instead of testosterone replacement therapy.
Long-term use of AAS in male bodybuilder may lead to secondary hypogonadism. This is because when AAS is added to the body, the brain mistakenly believes that the body is producing enough gonadal hormone to meet its needs and gradually reduces the release of endogenous testosterone. Hypogonadism occurs over a long period of time.
When the male bodybuilder ended the AAS cycle, endogenous testosterone levels decreased and estrogen levels increased. The body needs to readjust its hormone levels to achieve balance. Being out of balance in hormone levels for a long time can have a big impact on the body. SERM Clomid reduces estrogen levels and increases testosterone to help the body recover faster.
Gynecomastia occurs when estrogen levels are high in men for a long time. Clomid can treat gynecomastia, preventing men from developing irreversible breasts.
When testosterone levels in men remain low for a long time, it can lead to symptoms such as loss of libido, erectile dysfunction and fatigue. Clomid promotes the release of gonadotrophins from the brain, helping men restore their endogenous testosterone levels. The experiment showed that Clomid at 50mg/day increased testosterone levels by about 870ng/dL in young men and 490ng/dL in older men. In a study of men with low testosterone levels, treatment with clomid at 25mg per day for 3 months increased testosterone levels from 309ng per deciliter to 642ng per deciliter.
Since Clomid blocks estrogen and enhances gonadotropin release, this fertility treatment drug has become increasingly popular in bodybuilder. Clomid is already the preferred choice for bodybuilder pct cycle.