Buy Peptides Follistatin 344 Build Muscle 1mg/vial Good Price with High Quality

The product we’re talking about today is Follistatin 344. Follistatin 344 is an autocrine activin-binding protein that is expressed in almost all tissues of higher animals. So, when bodybuilder use Follistatin 344 build Muscle,  What does follistatin 344 have to do with muscle, and how does it build muscle?  

The following are follistatin 344 basic information:

Product Name:Follistatin 344
CAS: 80449-31-6
MF: C13H16O3
MW: 5135.78
Purity(by HPLC):>99.00%~99.90%
Total Impurities(by HPLC):1.00%~0.05%
Single Impurity(by HPLC):<0.50%~0.08%
Appearance:Sterile Filtered White Lyophilized (Freeze-Dried)
Purity:Above 98%
Packing:1mg/vial;10vials/box
Storage:Shading, confined preservation,2-8°C

I went to Wikipedia and searched for “Follistatin 344”. Unfortunately, I only found the word “Follistatin”, but I found that Follistatin 344 is actually a form of Follistatin. 

Follistatin forms

It is encoded in the following forms. Follistatin 288, Follistatin 300, Follistatin 315 and Follistatin 344, where the numbers represent amino acid counts.  

Follistatin 288: A follistatin that is primarily associate with reproductive health.  It also plays a role in tumor and cancer cell development  

Follistatin 300: Another follistatin, involved in remodeling nerve connections and heart inflammation  

Follistatin 315: The major follistatin form found in the blood.  It mainly targets muscle tissue.  

Follistatin 344: The most basic form of follistatin.  mainly use follistatin 344 in gene therapy, which uses a specially designed virus to inject a gene that helps produce more follistatin.  Different parts of the body can then convert this “general” form of follistatin into a more specific type to target different parts of the body. 

From the above coding forms, we can see that Follistatin 315 is mainly aim at muscle tissue.  So what’s the relationship between follistatin 344 build Muscle and Follistatin 315?  

We can further explore the gene characteristics of follistatin 344.  

The follistatin gene is localize on chromosome 5q11.2.  It consists of a relatively small 6-kb genomic DNA consisting of six exons.  An alternative splice site yields two major species, a full-length version encoding a 344-amino acid preprotein whose 27-amino acid sequence differs from its 317 amino acid carboxyl shortened version in the form of exon 6 deletion.  Prior to activation, after further posttranslational modification, an additional 29 amino acids, called short isomers, are lost by removing the signal peptide that produces the 315 (FS 315) polypeptide (commonly referre to as the long isoform and 288 (FS 288) polypeptide).  There is also evidence that FS 315 can be proteolytically cleaved at the carboxyl terminus in vivo to produce an intermediate isomer of 303 amino acids. 

According to the above genetic characteristics of follistatin, we can know that Follistatin 344 is activate in vivo to produce Follistatin 315 and Follistatin 288, among which Follistatin 315 mainly plays a role in muscle tissue.  Follistatin 288 is associate with reproductive health, among others.  Now we know why follistatin 344 build muscle. 

Follistatin 344 Build Muscle

In a study in 2014 , when healthy people took Follistatin 344 for eight weeks while undergoing a Bodybuilding program, follistatin 344 inhibited myostatin by 44 percent, increasing muscle growth threefold.  

Myostatin, which regulates the growth and differentiation of muscle cells and limits the growth of skeletal muscle, Follistatin 344 inhibits myostatin, liberates muscle and enables Bodybuilder to grow more muscle.  

Follistatin 344 stimulates the development of muscle cells, thereby promoting muscle growth and repair.  However, the experiment also found that follistatin 344 increased muscle growth even in mice genetically engineered to lack myostatin, suggesting that follistatin 344 build muscle in other ways than by acting on myostatin. 

FDA approved Follistatin 344 in 2012 as a safe product for the treatment of Becker and Duchenne muscular dystrophy.  

In order to achieve the purpose of muscle increase, Bodybuilder will use some supplements to complement bodybuilding. The commonly used supplements include androgen steroids and SARMs, etc. However, the long-term use of these supplements will bring some corresponding side effects.  Such as suppressing their testosterone levels, mental anxiety, etc.  Use Follistatin 344 build muscle, follistatin 344 as a peptide, at the same time, also from the genetic aspect of direct action on muscle, more safe.