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How to choose the right TRT dose?

09/25/2024

Is Testosterone replacement Therapy (TRT) a uniform dose? If everyone’s TRT dose is different, what is the basis for the right dose for everyone?

Select the appropriate TRT dose

Before starting TRT, the doctor will perform a thorough evaluation, including measuring serum testosterone levels (usually in the morning), and evaluating related symptoms (such as decreased libido, fatigue, mood changes, etc.). The needs and response to treatment vary from patient to patient, so the dose of TRT is different for everyone.

Initial dose

Different forms of TRT (such as injections, gels, patches, etc.) have different recommended starting doses. For example, injections of testosterone usually start at 50-100 mg per week, while gels may start at 50 mg per day. By following your doctor’s advice and choosing the right starting dose, you can avoid unwanted side effects.

Dose adjustment

During the first few months of treatment, doctors will regularly monitor the patient’s symptoms and testosterone levels to assess the effectiveness of the treatment.

If symptoms do not improve or testosterone levels do not reach the ideal range, the doctor may gradually increase the dose (usually 10-25% at a time) until reach the best results.

Monitor changes in testosterone levels

During the first few months of treatment, usually perform blood tests every 3-6 weeks to monitor testosterone levels and other relevant indicators (such as hemoglobin, red blood cell count, PSA levels, etc.).

Once testosterone levels are stable, they’ll reduce the frequency of testing to every 3-6 months or once a year, depending on the doctor’s recommendation and the patient’s health.

Assess symptom changes

Patients should pay attention to changes in their symptoms, including energy, libido, mood, and overall quality of life. These subjective feelings are important indicators to evaluate the effect of TRT.

A journal or table can be used to record changes in symptoms for discussion with your doctor.

Detection index

Monitor the Total and free testosterone levels, usually with the goal of staying within the normal range (usually 300-1000 ng/dL, but the specific range may vary from laboratory to laboratory).

Hemoglobin, hematocrit and PSA levels are also monitored to assess the presence of potential health problems.

Deal with side effects

Pay attention to possible side effects, such as skin problems, mood swings, increased red blood cells, etc., and communicate with your doctor promptly.

Depending on the severity of side effects, the doctor may adjust the dose or choose other forms of treatment.

Health assessment

Regular comprehensive health checks, including cardiovascular health, liver function, and prostate health, are required to ensure the safety of long-term treatment.

Choosing the right dose of TRT needs to be based on individual assessment, doctor’s advice, and regular monitoring. Through regular blood testing and symptom evaluation, patients and doctors can work together to adjust the dose to ensure efficacy and safety. Always perform TRT under the guidance of a medical professional for best results and to reduce risk.

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