Peptides Sermorelin acetate vs HGH to increase GH level, which one is better?

The effect of Sermorelin acetate vs HGH is similar. What is the specific situation and which one is more effective?

The same effects of Sermorelin acetate vs HGH

HGH is human growth hormone and is an anabolic peptide. It is regulated by growth hormone-releasing hormone (GHRH) secretion and stimulates human growth, cell reproduction and cell regeneration. In adults and bodybuilders, it helps increase metabolic levels and contributes to muscle growth and fat loss, thereby increasing lean muscle mass.

Sermorelin acetate is a type of growth hormone releasing hormone (GHRH) derived from 29 of the 44 amino acids of GHRH, retaining the ability of GHRH to stimulate GH release. Therefore, the use of Sermorelin acetate is mainly to stimulate the release of HGH and increase the level of HGH in the body, so Sermorelin acetate and HGH have similar effects.

The difference of Sermorelin acetate vs HGH

Whether they used Sermorelin acetate or HGH, they all played the role of HGH in the end. The most direct difference between them was the difference in the mode of action, one was to indirectly increase the level of HGH in the body, while the other was direct.

HGH

The use of HGH is to directly add exogenous HGH to improve the overall HGH level of the body, which bypasses the human body’s natural HGH production mechanism and improves the total HGH level, but does not improve the secretion of endogenous HGH. Therefore, it does not help the level of autocrine HGH. Even, by the automatic regulation of the human hormone balance, as the level of exogenous HGH increases, the secretion of endogenous HGH may decrease. Therefore, the use of HGH increases the overall level of HGH, increases the level of HGH available to the body, helps to play the beneficial role of HGH, but does not increase the level of autocrine HGH, and may reduce the level of endogenous HGH.

Sermorelin

Sermorelin acetate was used to bind to GHRH receptors to stimulate the secretion of HGH, which acted before HGH production and mimicked the natural production pattern of HGH. Compared with the direct supplement of exogenous HGH, regulated by the balance of human hormone levels, Sermorelin acetate could interact with somatostatin to promote the intermittent release of HGH after entering the human body, which was similar to the production pattern of natural HGH and more friendly to the human body, thus avoiding the possible tolerance reaction caused by the direct use of HGH. Studies have shown that using Sermorelin acetate allows the body to adjust to previous levels of HGH secretion, helping to improve the function of the component itself, rather than simply replacing the effect of HGH that the body is already lacking.

In conclusion, the use of Sermorelin acetate was more in line with the self-regulation of human hormones, and the increased HGH level was within a safe and controllable range. However, if you are after a level of HGH in a superphysiological dose, only exogenous HGH can do it.