What is Mesterolone, the Mesterolone feature?

What is Mesterolone?

It is better known by its brand name Proviron than Mesterolone.

Mesterolone is an oral androgen and anabolic steroid (AAS) drug developed in the 1960s and introduced for medical use by Schering in 1967 under the brand name Proviron. It is a derivative of DHT, does not produce estrogen, has weak androgenic and anabolic effects, is used primarily to treat low testosterone levels, and has also been used to treat male infertility.

Product Name: Mesterolone

Other name: Proviron

CAS : 1424-00-6

MF: C20H32O2

MW: 304.47

EINCES: 215-836-3

Purity: 99%Min

Appearance: White powder

Package: 10g/bag or as customers’request.

Test Method: HPLC

Mesterolone feature

Weak androgenic and anabolic effects of Mesterolone feature

Mesterolone is an androgen receptor (AR) agonist and has relatively low androgen and anabolic potency due to the inactivation of 3α-hydroxy steroid dehydrogenase (3α-HSD) in skeletal muscle tissue, similar to DHT and Mestanolone. However, it still shows a greater ratio of anabolic activity to androgen activity compared to testosterone.

Mesterolone feature of does not be converted to estrogen

Mesterolone is not a substrate for 5α-reductase because it has been reduced by 5α-reductase. Therefore, there is no enhancement in androgenic tissues such as skin, hair follicles, and prostate.

Mesterolone is not a substrate for aromatase and cannot be converted to estrogen. As a result, Mesterolone is not associated with estrogen side effects, such as gynecomastia and fluid retention.

Mesterolone feature of no hepatotoxicity

Mesterolone is not a 17α-alkyl compound, so it has no hepatotoxicity.

Mesterolone feature of can be taken orally

Mesterolone is not metabolized by the liver and has significant oral activity. Mesterolone is one of the few oral AAS that are either 17 alpha-alkylated or not. Mesterolone can be used in high doses or for longer periods of time depending on the individual situation.

Mesterolone feature of increasing serum free testosterone concentration

Mesterolone has a very high affinity for human serum sex hormone binding protein (SHBG), and therefore, it may replace endogenous testosterone in binding to SHBG, thereby increasing serum free testosterone concentration. Similarly, when Mesterolone is preferentially combined with SHBG, the activities of other AAS can be increased to make other AAS play their full role.